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Variant cover art by Nick Bradshaw
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1st appearance of Nova, Sam Alexander
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1st appearance of Kaine as the Scarlet Spider
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Death of Terrax the Tamer
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1st team appearance of X-Terminated: Horror Show, Fiend, Deadeye, Prophet, Goodnight
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[January 2021 - the MCU maintains their intention of using Nova (Alexander & Rider) in a movie]
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Debut of Doctor Strange from an alternate Earth with new costume design
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[February 2022 - In The Multiverse of Madness trailers shows a variant of Strange referred to as Defender Strange wearing the costume introduced in this issue / March 2022 - Deadline reports a source confirms a Nova project is in the development]
